Mixed Venous Oxygen Content (CvO2)
Mixed venous oxygen content (CvO2) is the amount of oxygen bound to hemoglobin (1.34 * Hb * SvO2) plus the oxygen dissolved in plasma (0.0031 * PvO2).
Mixed venous oxygen content equation: CvO2 = (1.34 * Hb * SvO2) + (0.0031 * PvO2).
The normal oxygen combining capacity is 1.39 mls/gram, however due to abnormal forms of hemoglobin such as carboxyhemoglobin and methemoglobin this value is reduced to 1.34 mls/gram.
Hgb is Hemoglobin, the normal Hgb for males is 14-20 g/dl and females 12-15 g/dl. Hgb expressed as g/dl is equivalent to g Hgb/100 mL of Blood.
SvO2 is the percentage of available hemoglobin that is saturated with oxygen, this value is from a direct measurement of an venous blood gas.
0.0031 is the solubility coefficient of oxygen at body temperature.
PvO2 is the mixed venous oxygen tension.
Mixed Venous Oxygen Content – CvO2 Calculator
Mixed Venous Oxygen Tension: PvO2 in mmHg
Hemoglobin Saturation: SvO2 in %
Hemoglobin: Hgb in g/dl (g Hgb/ 100 mL Blood)
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